Tag Archives: incredible

Real life 23-year-old game of “tag” to be turned into a motion picture

For 23 years, a group of friends from Washington state have been playing a game of tag. It started in high school, and went through college. Rules eventually developed that turned it into a no-holds-barred, nationwide game that goes on every year throughout the month of February. Who ever is “it” will travel all over the country to tag one of their competitors, sometimes creating elaborate schemes to do so. Whoever is “it” at the end of the month is “it” for the whole year.

In January, the novel idea caught the interest of a Wall Street Journal reporter who turned it into a human interest story. Since then, the Tag Brothers, as they’ve been coined, have been fielding pitches from Hollywood producers who want to turn their real life game into a movie.

Wednesday, the Tag Brothers sold the rights to their story to Broken Road producer Todd Garner. He’ll create a pitch and take it to Hollywood studios.

Deadline broke the news of the deal, which apparently was a fairly hot property among Hollywood producers.

This story screams “high-concept comedy” with an all-star cast and it makes perfect sense that producers took notice. You can read the full Wall Street Journal article at this link, but the gist is as follows. Ten friends attending high school at Gonzaga Preparatory School in Spokane, Washington began playing tag and never stopped. The game continued to grow and grow and has gotten to the point where now, 23 years later, it can get expensive and elaborate.

Everything is normal all year until February. At that point, the men have been known to travel, set up pranks, hire people to play roles and more just to be able to tag one of the other competitors and make him “it.”

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FDA approves the first drug to prevent HIV

I’ve posted a few stories on this site about the many breakthroughs in preventing HIV, but today I’m happy to write this post. Yesterday the FDA approved Truvada, the very first drug approved by the FDA for the prevention of HIV. It is a huge step in eradicating the world of one of the most horrifying diseases there is.

When taken daily, Truvada (emtricitabine/tenofovir disoproxil fumarate) reduced the risk of HIV infection by 42 percent compared with a placebo. That was in a clinical trial where HIV-negative individuals had unprotected sex with multiple partners, including some HIV carriers, according to the FDA. Another trial involving heterosexual couples where one partner was infected — and condoms were used routinely — found that Truvada reduced the risk of infections by 75 percent.

“The data clearly demonstrate that Truvada as pre-exposure prophylaxis is effective at reducing the risk of HIV infection acquired through sexual exposure,” said Dr. Connie Celum, a professor of global health and medicine at the University of Washington who led the trial involving heterosexual couples. “It is exciting to consider the potential impact of this new HIV prevention tool, which could contribute to significantly reducing new HIV infections as part of a combination HIV prevention strategy.”

Truvada is already approved to be used in combination with other antiretroviral drugs for the treatment of HIV.

For prevention purposes, the drug should be used along with other prevention methods, the FDA said in a press statement, such as safe sex practices, risk reduction counseling, and regular HIV testing.

“Today’s approval marks an important milestone in our fight against HIV,” FDA Commissioner Dr. Margaret Hamburg said in a statement. “Every year, about 50,000 U.S. adults and adolescents are diagnosed with HIV infection, despite the availability of prevention methods and strategies to educate, test, and care for people living with the disease.”

The most common side effects reported with Truvada included diarrhea, nausea, abdominal pain, headache, and weight loss. In rare cases, the drug may cause kidney problems or bone toxicity.

As a condition of approval, the FDA is requiring Truvada’s manufacturer, Gilead Sciences, to study those who acquire HIV while taking Truvada to determine if anyone can develop a resistance to the drug. The company also needs to collect data on women who become pregnant while taking the drug since safety risks to the fetus remain unknown.

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Genius

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THE BEST NEWS EVER: BILL MURRAY ANNOUNCES US PARTY CRASHING TOUR!

Bill Murray party crashing tour

Bill Murray has been known to crash random parties in NYC and a couple other cities in the US. Most reports say that he always brings something to offer the host, is incredible nice and polite, and has a great time with almost everyone. I’ve always wanted, more than anything, to have a chance to party with Bill Murray, but as you can imagine, I didn’t think I would ever get the chance being that he typically only does it in NYC. A few days ago however, I read a story about Bill Murray doing a national party crashing tour and my hopes and dreams were reignited. Although Bill himself hasn’t spoken to the press, his agent, Paul Horner, gave out the details, as well as the tour schedule, and you can take a guess as to when I’ll be in Minneapolis.

Mr. Murray did not speak to reporters but did have his agent Paul Horner answer some of their questions and make a few statements. “Mr. Murray is looking to take a vacation around the United States. He’s hoping that if he shows up to your party with a bottle of wine or vegetable tray, you will be able to make the proper accommodations for him. This includes allowing him to sleep on your couch or in a spare bedroom, both of those options being completely acceptable.”

Now in order for Bill Murray to come crash your party, his agent says that there are a few conditions:

Horner continued to explain some of the conditions of the tour to reporters. “All we ask is that if Mr. Murray does decide to crash your party, please give him his space. He’s a human being, just like you and me. He’s just looking for a good time and a fun way to connect with fans.” Horner then went on to explain more details about the tour, “At these parties, Mr. Murray does not want to be called ‘Bill Murray’ but instead wants to be referred to as ‘Kaiser Soze’. Activities that Mr. Murray enjoys are drinking and karaoke. Having those two things at your party will definitely increase your chances of him making an appearance. Also it is extremely important that any house or location interested in participating have a sheet or banner of some kind attached to their establishment the night of the party. It must say in big bold letters, ‘BILL MURRAY CAN CRASH HERE’. This will let Mr. Murray know at what locations he is welcome.”

The Bill Murray Party Crashing Tour will kick off August 1st in Phoenix, Arizona and will end September 10th in Austin, Texas.

Now lets all call the Bill Murray Party Crashing Tour Hotline: (785) 273-0325 and tell him to come to Madison, WI for a night or two, eh?

Bill Murray Party Crashing Tour signs

Bill Murray Party Crashing Tour signs

Bill Murray Party Crashing Tour signs

Bill Murray can crash here signs

Bill Murray can crash here signs

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Science! Soon your poop will tell you what is wrong with you!

If you have been waiting for the day when you could finally just look at your poop instead of going to the doctor to figure out what the hell is going on in your stomach, you may not have to wait much longer. E. chromi is a new probiotic yogurt drink that actually changes the color of your feces in order to communicate any stomach ailments you may have. Although it is only used to detect E. coli today, in the very near future it will be able to detect the above viruses and such, with magic colorful poop power.

While researchers have so far only suggested that the drink could be used to track the progress of E. coli, they believe that one day it can diagnose conditions like colorectal cancer, worms, stomach ulcer and salmonella just by people looking into the toilet to check the color of their remains.

British designers Alexandra Daisy Ginsberg and James King developed the disease detecting drink by first genetically engineering bacteria to secrete a variety of colored pigments that are visible to the naked eye.

The team had designed standardized sequences of DNA, known as BioBricks, and inserted them into E. coli bacteria. They explain that each BioBrick part contains genes selected from a range of existing organisms that allows the bacteria to produce colors like red, yellow, green, blue, brown or purple.

They explained that by combining these with other BioBricks, bacteria could be programmed to do things like indicate whether water or food is safe to drink or eat by turning red if they sense a toxin.

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Guy builds a Mad Max style motorcycle from car parts after his car breaks down in the middle of the desert

File this under “Seriously bad ass can’t be killed motherfuckers”… a guy is driving through the desert and his car breaks down. Instead of crying and wandering through the desert on foot, leading to his ultimate demise, he takes the car apart and turns it into a fucking motorcycle.

While traveling through the desert somewhere in north west Africa in his Citroen 2CV , [Emile] is stopped, and told not to go any further due to some military conflicts in the area. Not wanting to actually listen to this advice, he decides to loop around, through the desert, to circumvent this roadblock.

After a while of treading off the beaten path, [Emile] manages to snap a swing arm on his vehicle, leaving him stranded. He decided that the best course of action was to disassemble his vehicle and construct a motorcycle from the parts. This feat would be impressive on its own, but remember, he’s still in the desert and un-prepared. If we’re reading this correctly, he managed to drill holes by bending metal and sawing at it, then un-bending it to be flat again.

More here

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New viral video for Prometheus is absolutely brilliant

Just fucking brilliant, I will see this movie because of this video alone.

 

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